Advances in molecular technologies, imaging, and AI have increased the precision of cancer diagnosis. As the number of cancer diagnoses increases, more and more people will require access to essential surgery, the primary frontline treatment for many cancer types. Unfortunately, nine out of ten people in developing countries do not have access to basic surgical care, which requires skill and experience. Ethanol ablation, the direct injection of pure ethanol into tissue to induce cell death, is a low-cost alternative to surgery. Our team has developed a novel ablation method for cancer control that combines the precision of energy-based ablation technologies and the simplicity and cost-effectiveness of ethanol.